Santa Cruz Vacation Packages
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Your Santa Cruz Vacation
With one of our vacation packages to Santa Cruz, you'll find countless opportunities for adventure and relaxation. There's so much to experience, including its beaches and lively atmosphere. If taking in sights is part of the program during your trip to Santa Cruz, check out major attractions like Plaza 24 de Septiembre, Guembe Biocenter and Ventura Mall. Whoever you're heading away with and whatever the size of your budget, your dream Santa Cruz vacation is just clicks away with Expedia.
Where to stay in Santa Cruz
Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz
Equipetrol
Though Equipetrol might not have many top sights, you can venture to the surrounding area to see attractions like Santa Cruz Zoo and Municipal Library.
Centro Histórico
3 out of top 10 points of interest in this area
If you're spending some time in Centro Histórico, Plaza 24 de Septiembre and La Recova Artisan Walk are top sights worth seeing.
Hamacas
While Hamacas isn't home to many top sights, Las Brisas Shopping Center and Santa Cruz Zoo are some notable places to visit nearby.
Zona Sur (South Zone)
Zona Sur (South Zone) might not have many top sights, but Ramon Tahuichi Aguilera Stadium and Plaza 24 de Septiembre are two attractions nearby that you can check out.
Urubó
While Urubó might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Guembe Biocenter and Ventura Mall.
Ready to book your vacation to Santa Cruz?
Santa Cruz Hotel Deals
Ibis Santa Cruz DE LA Sierra
AVENIDA CRISTOBAL DE MENDOZA Santa Cruz
CA $55
CA $55 total
Oct 17 - Oct 18
9.4/10 Exceptional! (150 reviews)
"The hotel is OK, but nothing more. Stuff was unpleasant"
Reviewed on Sep 24, 2026
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Ave. San Martin, #455 Santa Cruz
CA $215
CA $215 total
Nov 3 - Nov 4
Marriott Santa Cruz de la Sierra Hotel
4to Anillo Entre Radial 23 Santa Cruz Santa Cruz
CA $150
CA $150 total
Nov 1 - Nov 2
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Santa Cruz attractions
Plaza 24 de Septiembre
8.8/10 (164 reviews)
The heart of Santa Cruz lies in this public square, where locals relax and tourists sightsee in a welcoming, laid-back atmosphere.
San Lorenzo Cathedral
9.0/10 (84 reviews)
One of the most iconic landmarks in Santa Cruz is the city’s mighty cathedral, which houses a museum displaying important artwork.
Ventura Mall
9.0/10 (183 reviews)
During your visit to Santa Cruz, you can find the perfect gifts to bring home at Ventura Mall. Make some time to visit the cathedral while you're in the area.
Guembe Biocenter
8.8/10 (60 reviews)
Explore the great outdoors at Guembe Biocenter, a lovely green space in Colinas del Urubo. While in the area, you can find time to visit its shops.
Ramon Tahuichi Aguilera Stadium
8.4/10 (18 reviews)
Catch an event at Ramon Tahuichi Aguilera Stadium during your trip to Santa Cruz. While in the area, you can find time to visit its shops.
Las Brisas Shopping Center
8.4/10 (40 reviews)
You can find the perfect gifts to bring home at Las Brisas Shopping Center during your visit to Santa Cruz. While in the area, you can find time to visit its shops.
Santa Cruz Zoo
8.4/10 (53 reviews)
Why not visit the native and exotic animals who call Santa Cruz Zoo home during your vacation in Santa Cruz? While in the area, you can find time to visit its shops.
Blacutt Square
8.2/10 (19 reviews)
Find out about the history of Santa Cruz when you spend time at Blacutt Square. While in the area, you can find time to visit its shops.
What to do in Santa Cruz
Santa Cruz and Porongo: History, Markets, River, and Culture
CA $140
per adult
Samaipata Fort Tour: Ancient Ruins in 1 Full Day
CA $418
per adult
4D/3N Expedition: Che Guevara Route - Disconnect from the World
CA $1,118
per adult
Frequently asked questions
How much does a Santa Cruz vacation package cost?
Offering excellent value package deals on Expedia, you'll be surprised at how little a vacation to Santa Cruz costs! Our packages mean less travel planning for you and greater savings.
What are the cheapest months to go to Santa Cruz?
If you're hoping to score a cheap Santa Cruz vacation package, consider planning a trip in February, April and May. You're likely to find lower prices on accommodations and flights during these months — ideal for travellers wishing to save money.
How many days is enough for Santa Cruz?
With a well-organized travel plan, you can easily tick off the most popular Santa Cruz attractions in a handful of days. But if you'd like to discover hidden spots or go on day trips, think about booking your Santa Cruz vacation for longer.
Is it worth booking a vacation package to Santa Cruz?
Santa Cruz is a good vacation destination with attractions like Ventura Mall among the many things to keep you busy. Whether you're travelling with the family or planning a trip with friends, a Santa Cruz vacation promises fun for everyone.
How to find the best Santa Cruz package deals?
Begin your search for a Santa Cruz package deal by entering your destination and preferred travel dates under our "Packages" tab. Then apply a few filters, like "Property type" and "Amenities," to tailor the results to your exact needs. You can also sort by "Package discount" and discover offers that come with big savings. If you don't find the perfect Santa Cruz package deal right away, simply play around with your dates and search again. Remember that deals are only available for a limited time, so book early and get your Santa Cruz adventure off to a flying start.
Is it cheaper to book a Santa Cruz vacation as a package?
Expedia vacation packages are designed to give you more bang for your buck. Bundle your hotel, flight and car rental into one great-value price and enjoy significant savings. You'll usually land a better deal than booking each component separately. And you'll still enjoy the flexibility to create a customized Santa Cruz vacation by choosing your favourite type of stay, airline and car class.
When to book a vacation package to Santa Cruz?
If you're planning a spontaneous Santa Cruz getaway, browse our last-minute deals that can be booked up to a week before you go. Don't want to leave things to the last minute? You can find terrific deals on your flights and hotels by booking ahead.
How to plan a trip to Santa Cruz?
- Choose your dates: What you'd like to do in Santa Cruz and your preferred season can help you decide when to travel.
- Figure out your budget: Ensure you have enough money to pay for everything from food and transportation to activities and airfares. Your hotel will likely be the largest expense during your trip to Santa Cruz.
- Decide your trip length: Think about how long you'd like to spend discovering Santa Cruz. Plan your itinerary so you can get to all the experiences and attractions you're interested in at a leisurely pace.
- Combine your accommodations and airfare: Once you've settled on your travel dates and duration, book the right Santa Cruz vacation package for you.
Explore a world of travel with Expedia
- Hotels with Hot Tubs in Santa Cruz
- Los Tajibos
- Hamacas Hotels
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- Senses Boutique Hotel
- Treehouses in Santa Cruz
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- Hotels near Viru Viru Intl.
- Apartments in Santa Cruz
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- Alfonsina Hotel Boutique by Inboccaluppo
- Senses Centro
- Hotel La Quinta
- Hotels with a Pool in Santa Cruz
- Shopping Hotels in Santa Cruz
- Flights from Miami (MIA) to Santa Cruz (VVI)
- Flights from Las Vegas (LAS) to Santa Cruz (SRZ)
- Flights from Edmonton (YEA) to Santa Cruz (SRZ)
- Flights from Edmonton (YEG) to Santa Cruz (SRZ)
- Flights from Orlando (ORL) to Santa Cruz (SRZ)
- Flights from Upland (CCB) to Santa Cruz (SRZ)
- Flights from Regina (YQR) to Santa Cruz (VVI)
- Flights from Santa Maria (SMX) to Santa Cruz (SRZ)
- Flights from Shanghai (SHA) to Santa Cruz (SRZ)
- Flights from Calgary (YYC) to Santa Cruz (VVI)
- Flights from Vancouver (YVR) to Santa Cruz (VVI)
- Boliviana De Aviacion Miami (MIA) to Santa Cruz (VVI) flights
- Flights from Ottawa (YOW) to Santa Cruz (VVI)
- Flights from Victoria (YYJ) to Santa Cruz (SRZ)
- Flights from Santiago (SCL) to Santa Cruz (VVI)
- Flights from San Francisco (SFO) to Santa Cruz (SRZ)
- Flights from Beirut (BEY) to Santa Cruz (SRZ)
- Flights from Birmingham (BHM) to Santa Cruz (SRZ)
- Flights from Dhaka (DAC) to Santa Cruz (SRZ)
- Flights from Grand Rapids (GRR) to Santa Cruz (SRZ)
- Flights from Ottawa (YRO) to Santa Cruz (SRZ)
- Flights from Lima (LIM) to Santa Cruz (VVI)
- Flights from Madison (MSN) to Santa Cruz (SRZ)
- Flights from Quito (UIO) to Santa Cruz (VVI)
- Flights from Lagos (LOS) to Santa Cruz (SRZ)
- Flights from Las Vegas (LAS) to Santa Cruz (VVI)
- Flights from Kelowna (YLW) to Santa Cruz (SRZ)
- Flights from Victoria (YYJ) to Santa Cruz (VVI)
- Flights from Winnipeg (YWG) to Santa Cruz (VVI)
- Flights from Saskatoon (YXE) to Santa Cruz (SRZ)
- Flights from Montreal (YUL) to Santa Cruz (VVI)
- Flights from Lafayette (LFT) to Santa Cruz (SRZ)
- Flights from San Francisco (SFO) to Santa Cruz (VVI)
- Flights from Madrid (MAD) to Santa Cruz (VVI)
- Flights from Viru Viru Intl.
- Flights from Winnipeg (YWG) to Santa Cruz (SRZ)
- Flights from Fort Saint John (YXJ) to Santa Cruz (SRZ)
- Flights from São Paulo (GRU) to Santa Cruz (VVI)
- Flights from La Paz (LPB) to Santa Cruz (VVI)
- Flights from La Serena (LSC) to Santa Cruz (VVI)
- Flights from Winter Haven (GIF) to Santa Cruz (SRZ)
- Flights from Calgary (YYC) to Santa Cruz (SRZ)
- Flights from Spokane (GEG) to Santa Cruz (SRZ)
- Flights from Osaka (KIX) to Santa Cruz (SRZ)
- Flights from Bogotá (BOG) to Santa Cruz (VVI)
- Flights from Fort Collins (FNL) to Santa Cruz (SRZ)
- Flights to Santa Cruz
- Flights from Curitiba (BFH) to Santa Cruz (SRZ)
- Flights from Puerto Vallarta (PVR) to Santa Cruz (SRZ)
- Flights from Kelowna (YLW) to Santa Cruz (VVI)
- Flights from New York (JFK) to Santa Cruz (VVI)
- Flights from Los Angeles (LAX) to Santa Cruz (VVI)
- Flights from Detroit (DTW) to Santa Cruz (VVI)
- Flights from Manila (MNL) to Santa Cruz (SRZ)
- Flights from Panama City (PTY) to Santa Cruz (VVI)
- Flights from Mexico City (MEX) to Santa Cruz (SRZ)
- Flights from Vancouver (YVR) to Santa Cruz (SRZ)
- Flights from Saskatoon (YXE) to Santa Cruz (VVI)
- Flights from Halifax (YHZ) to Santa Cruz (VVI)
- Flights from Cancun (CUN) to Santa Cruz (SRZ)
- Flights from San Luis Obispo (SBP) to Santa Cruz (SRZ)
- Flights from Toronto (YYZ) to Santa Cruz (SRZ)
- Flights from Norfolk (ORF) to Santa Cruz (SRZ)
- Flights from Palm Springs (PSP) to Santa Cruz (SRZ)
- Flights from San Cristobal (SCY) to Santa Cruz (VVI)
- Flights from Buffalo (BUF) to Santa Cruz (SRZ)
- Flights from Indianapolis (IND) to Santa Cruz (SRZ)
- Flights from Arica (ARI) to Santa Cruz (SRZ)
- Flights from Montreal (YUL) to Santa Cruz (SRZ)
- Flights from Toronto (YYZ) to Santa Cruz (VVI)
- Flights from Edmonton (YEG) to Santa Cruz (VVI)
- Flights from Raleigh (RDU) to Santa Cruz (SRZ)
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
